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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">Dear Colleagues, </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">We warmly invite submissions to the <b>Mathematical Foundations in Bioinformatics (MatBio) 2021</b> special issue of the </span><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(32, 31, 30)">Journal
of Computational Biology</span><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)"> according to the following call for papers.</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48);background-color:white">The MatBio conference series was founded in 2016, with conferences held annually in London since then. The 2021 conference was on<span class="x_Apple-converted-space" style="margin:0px"> </span></span><a href="https://nms.kcl.ac.uk/informatics/events/MatBio2021/" target="_blank" rel="noopener noreferrer" data-auth="NotApplicable" data-linkindex="0" style="margin:0px;color:rgb(149, 79, 114);text-decoration:underline"><span style="margin:0px;font-family:"Times New Roman", serif;background-color:white">Sept
2021</span></a><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48);background-color:white">, and we welcome your contribution to this special issue in its place.</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"><br>
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<span style="margin:0px;background-color:white"> </span></span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(32, 31, 30)"> </span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">*******************************</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">CALL FOR PAPERS: </span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">******************************* </span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">This special issue on </span><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(32, 31, 30)">the <b>Journal
of Computational Biology</b> </span><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">will be devoted to topics on novel algorithms for biological sequence and structure analysis, phylogeny
reconstruction, and combinatorial algorithms. Submissions presenting original research within these areas are invited. </span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(32, 31, 30)"> </span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">Topics of interest include but are not limited to:</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
<p class="x_MsoNormal" style="margin:0cm 0cm 0.0001pt;font-size:medium;font-family:Calibri, sans-serif;text-align:justify;background-color:white">
<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)"> </span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">* Algorithms and Data Structures</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
<p class="x_MsoNormal" style="margin:0cm 0cm 0.0001pt;font-size:medium;font-family:Calibri, sans-serif;background-color:white">
<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">* Complexity Theory</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
<p class="x_MsoNormal" style="margin:0cm 0cm 0.0001pt;font-size:medium;font-family:Calibri, sans-serif;background-color:white">
<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">* Graph Theory & Combinatorics</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
<p class="x_MsoNormal" style="margin:0cm 0cm 0.0001pt;font-size:medium;font-family:Calibri, sans-serif;background-color:white">
<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">* Combinatorial Optimization</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">* Sequence analysis</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">* Online Algorithms</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
<p class="x_MsoNormal" style="margin:0cm 0cm 0.0001pt;font-size:medium;font-family:Calibri, sans-serif;background-color:white">
<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">* Streaming Algorithms</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
<p class="x_MsoNormal" style="margin:0cm 0cm 0.0001pt;font-size:medium;font-family:Calibri, sans-serif;text-align:justify;background-color:white">
<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">* Big data</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
<p class="x_MsoNormal" style="margin:0cm 0cm 0.0001pt;font-size:medium;font-family:Calibri, sans-serif;text-align:justify;background-color:white">
<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">* Biostatistics</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
<p class="x_MsoNormal" style="margin:0cm 0cm 0.0001pt;font-size:medium;font-family:Calibri, sans-serif;text-align:justify;background-color:white">
<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">* Image analysis</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">* Network and graph models</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
<p class="x_MsoNormal" style="margin:0cm 0cm 0.0001pt;font-size:medium;font-family:Calibri, sans-serif;text-align:justify;background-color:white">
<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">* Scientific data management and data mining</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
<p class="x_MsoNormal" style="margin:0cm 0cm 0.0001pt;font-size:medium;font-family:Calibri, sans-serif;text-align:justify;background-color:white">
<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">* Machine learning</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
<p class="x_MsoNormal" style="margin:0cm 0cm 0.0001pt;font-size:medium;font-family:Calibri, sans-serif;text-align:justify;background-color:white">
<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">* Pattern recognition</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
<p class="x_MsoNormal" style="margin:0cm 0cm 0.0001pt;font-size:medium;font-family:Calibri, sans-serif;text-align:justify;background-color:white">
<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">* Computational evolutionary biology</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
<p class="x_MsoNormal" style="margin:0cm 0cm 0.0001pt;font-size:medium;font-family:Calibri, sans-serif;text-align:justify;background-color:white">
<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">* Computational genomics</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">------------------------------------------------------------------------------</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(32, 31, 30)"> </span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">** Papers which are pure theory, theory supported by experimentation, and applied research are encouraged. </span></p>
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<span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">** Papers must contain previously unpublished material.</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">** Survey papers which are relevant to the topics of the special issue are welcome and will be considered at the discretion of the editors.</span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">** All submitted papers will be refereed according to the usual Journal of Computational Biology refereeing process, namely a minimum
of two reviews but usually three. </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(50, 49, 48);background-color:rgb(255, 252, 0)"><br>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)">** To begin your submission, please go directly to </span><span style="margin:0px;color:black"><a href="https://mc.manuscriptcentral.com/jcb" target="_blank" rel="noopener noreferrer" data-auth="NotApplicable" data-linkindex="1" style="margin:0px;color:rgb(149, 79, 114);text-decoration:underline"><span style="margin:0px;color:rgb(25, 25, 25)">https://mc.manuscriptcentral.com/jcb</span></a></span><span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)">.
If you do not have an account, you will need to create one. Once you are signed in, click on “Author” and “Start New Submission.” From there, you will be prompted for specific information regarding the paper (title, etc.). Under Manuscript Type, you must
select “MatBio 2021” from the drop-down menu.<span lang="AR-SA" dir="RTL" style="margin:0px"> </span></span></p>
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<span lang="AR-SA" dir="RTL" style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)"> </span></p>
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<span dir="LTR" style="margin:0px"></span><span dir="LTR" style="margin:0px"></span><span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)"><span dir="LTR" style="margin:0px"></span><span dir="LTR" style="margin:0px"></span><span style="margin:0px"> </span>Please
visit the Instructions for Authors at </span><span style="margin:0px;color:black"><a href="https://home.liebertpub.com/publications/journal-of-computational-biology/31/for-authors" target="_blank" rel="noopener noreferrer" data-auth="NotApplicable" data-linkindex="2" style="margin:0px;color:rgb(149, 79, 114);text-decoration:underline"><span style="margin:0px;color:rgb(25, 25, 25)">https://home.liebertpub.com/publications/journal-of-computational-biology/31/for-authors</span></a></span><span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)"> for
complete details to prepare your manuscript.<br>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)">** Manuscripts must be prepared in either LaTex format or Microsoft Word.<span style="margin:0px"> <span class="x_Apple-converted-space" style="margin:0px"> </span></span><br>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)">The entire manuscript must be double spaced, Font size 12, including references and tables. Clearly identify unusual or Greek letters. </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)"> </span></p>
<p style="margin:0cm 0cm 0.0001pt;font-size:medium;font-family:"Times New Roman", serif;line-height:12.65pt;background-color:white">
<span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)">The Main Document generally includes: </span></p>
<ol start="1" type="1" style="background-color:rgb(255, 255, 255);margin-bottom:0cm;font-family:-webkit-standard">
<li class="x_MsoNormal" style="color:rgb(25, 25, 25);background:white"><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif">Title Page- Title, Authors & Affiliations [include all email(s)], Running Head </span></li><li class="x_MsoNormal" style="color:rgb(25, 25, 25);background:white"><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif">Abstract- 250 words or less with 5 Keywords </span></li><li class="x_MsoNormal" style="color:rgb(25, 25, 25);background:white"><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif">Introduction </span></li><li class="x_MsoNormal" style="color:rgb(25, 25, 25);background:white"><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif">Methods </span></li><li class="x_MsoNormal" style="color:rgb(25, 25, 25);background:white"><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif">Results </span></li><li class="x_MsoNormal" style="color:rgb(25, 25, 25);background:white"><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif">Discussion </span></li><li class="x_MsoNormal" style="color:rgb(25, 25, 25);background:white"><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif">Acknowledgements/Disclosure/Conflict of Interest Statements </span></li><li class="x_MsoNormal" style="color:rgb(25, 25, 25);background:white"><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif">References in JCB specified format (LaTex template available upon request) </span></li><li class="x_MsoNormal" style="color:rgb(25, 25, 25);background:white"><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif">Tables (1 per page) </span></li><li class="x_MsoNormal" style="color:rgb(25, 25, 25);background:white"><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif">Figure Legends </span></li><li class="x_MsoNormal" style="color:rgb(25, 25, 25);background:white"><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif">Figures (You may save as TIF, EPS, Word, PPT, PDF, PNG, JPG.<span style="margin:0px"> <span class="x_Apple-converted-space" style="margin:0px"> </span></span>Figures
should be clear; resolution for TIF And EPS files are typically 300 dpi resolution.<span style="margin:0px"> <span class="x_Apple-converted-space" style="margin:0px"> </span></span>Label each file with the author's last name and Figure number.<span style="margin:0px"> </span>Ex.
Smith Figure 1 </span></li></ol>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)">For LaTex Submissions: (Please contact the Editorial Office for LaTex templates)<br>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)">2 Options for uploading files (2nd one is preferred): </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)">1. Upload the main LaTeX file first, selecting the file designation of Main Document. </span></p>
<p style="margin:0cm 0cm 0.0001pt 36pt;font-size:medium;font-family:"Times New Roman", serif;background-color:white">
<span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)">Then, upload each file that is related to the main.TEX file as is needed for processing, selecting the file designation of TeX/LaTeX Suppl File. </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)">Be sure to upload all style sheets, and reference and bibliography files that are a part of the document. </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)">All figure/ image files must be saved and uploaded in .EPS format in order for the file to properly format and convert. </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)">Check the system-generated PDF of your manuscript, if not all characters convert properly, use the 2nd option below. </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)"> </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)">2. Authors may choose to upload a complete, full text (including figures and tables) PDF under the file designation "Full Manuscript PDF". </span></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;color:rgb(25, 25, 25)">The LaTex source files should be uploaded as a zip file as supplementary data, with the zip file name "SourceFiles.zip". </span></p>
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<b><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">The preliminary schedule:</span></b><b><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></b></p>
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<span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(32, 31, 30)"> </span><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></p>
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<span style="margin:0px;color:black">** Receipt of articles for the special issue is due by <b><u>November 1, 2021</u></b>.</span><span style="margin:0px"> </span></p>
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<span style="margin:0px;font-family:"Times New Roman", serif;color:black">** We will do our best to achieve a thorough and fast review process and publish this issue by<span class="x_Apple-converted-space" style="margin:0px"> </span><b><u>late 2022</u></b>.</span><span style="margin:0px;font-family:"Times New Roman", serif"> </span></p>
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<b><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">Best Regards from the Guest Editors, </span></b></p>
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<b><span style="margin:0px;font-family:"Times New Roman", serif;color:rgb(50, 49, 48)"> </span></b></p>
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<b><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">Dr<span class="x_Apple-converted-space" style="margin:0px"> </span><span style="margin:0px"> </span>Mai Alzamel | King’s College London </span></b></p>
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<b><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)"> </span></b></p>
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<b><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">Dr Christopher Hampson | King’s College London </span></b></p>
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<b><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">Prof<span style="margin:0px"> </span>Costas Iliopoulos | King’s College London </span></b></p>
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<b><span style="margin:0px;padding:0cm;border:1pt none windowtext;font-family:"Times New Roman", serif;color:rgb(25, 25, 25)">Dr<span class="x_Apple-converted-space" style="margin:0px"> </span><span style="margin:0px"> </span>Fatima Vayani | King’s College
London </span></b></p>
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